Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | RPS6KB2 | Q9UBS0 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861013 | 0.85 | MAPT (0.52) | DHFRRPS6KB2NPC1RAB9AMAPT | |
| SCHEMBL27658392 | 0.79 | KMT2A (0.54) | DHFRNPC1RAB9AGLAKDM4E | |
| SCHEMBL6047030 | 0.77 | KCNH2 (0.41) | NPC1RAB9AGLAKDM4EMAPT | |
| SCHEMBL2860819 | 0.75 | DHFR (0.54) | DHFRRPS6KB2NPC1RAB9AGLA | |
| SCHEMBL2857745 | 0.74 | TDP1 (0.44) | NPC1RAB9AGLAKDM4ETP53 | |
| SCHEMBL6237894 | 0.73 | RPS6KB2 (0.64) | DHFRRPS6KB2NPC1RAB9AGLA | |
| SCHEMBL27643402 | 0.72 | NPC1 (0.45) | DHFRRPS6KB2NPC1RAB9AGLA | |
| SCHEMBL6387970 | 0.71 | KMT2A (0.51) | DHFRNPC1RAB9AGLAKDM4E | |
| SCHEMBL2854976 | 0.71 | ALDH1A1 (0.48) | DHFRNPC1RAB9AKDM4ETP53 | |
| SCHEMBL2862807 | 0.71 | MEN1 (0.49) | DHFRRPS6KB2NPC1RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803898-B2 | Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090030176-A1 | Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1705178-A1 | AMINOQUINOXALINE COMPOUND, POLYAMINOQUINOXALINE COMPOUND, AND USE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030176-A1 | Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof | PAM, CYC1, QPCT | DHFR 721/4885RPS6KB2 2828/4885NPC1 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.