Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853061 | 0.94 | KDM4E (0.44) | P2RX7CCR1MAPTABCB1KDM4E | |
| SCHEMBL2858011 | 0.94 | ABCB1 (0.51) | P2RX7CCR1MAPTABCB1NPSR1 | |
| SCHEMBL2854340 | 0.93 | CCR1 (0.53) | P2RX7CCR1MAPTKDM4ENPSR1 | |
| SCHEMBL2857996 | 0.92 | CCR1 (0.48) | P2RX7CCR1MAPTABCB1KDM4E | |
| SCHEMBL2854346 | 0.91 | MAPT (0.52) | P2RX7CCR1MAPTKDM4ELMNA | |
| SCHEMBL2852556 | 0.90 | TDP1 (0.44) | CCR1MAPTKDM4ENPSR1 | |
| SCHEMBL2863154 | 0.90 | MAPT (0.45) | P2RX7CCR1MAPTKDM4ELMNA | |
| SCHEMBL2852941 | 0.89 | POLB (0.44) | CCR1MAPTKDM4ELMNAHTT | |
| SCHEMBL2856562 | 0.87 | MAPT (0.48) | P2RX7MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL2855493 | 0.87 | P2RX7 (0.48) | P2RX7CCR1MAPTNPSR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |