Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853061 | 0.94 | KDM4E (0.44) | POLBCCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2854509 | 0.91 | KDM4E (0.50) | POLBCCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2856562 | 0.89 | MAPT (0.48) | POLBMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2854346 | 0.89 | MAPT (0.52) | POLBCCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2862820 | 0.89 | P2RX7 (0.45) | CCR1MAPTKDM4ESMN1; SMN2MAPK14 | |
| SCHEMBL2852671 | 0.89 | MAPT (0.43) | POLBMAPTKDM4EALDH1A1KEAP1 | |
| SCHEMBL2857230 | 0.86 | KDM4E (0.44) | POLBCCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2863198 | 0.86 | CCR1 (0.50) | POLBCCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2858011 | 0.86 | ABCB1 (0.51) | CCR1MAPTTAAR1LMNA | |
| SCHEMBL2852221 | 0.86 | ALDH1A1 (0.46) | POLBMAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |