Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792537 | 0.90 | LMNA (0.42) | LMNAMAPTL3MBTL1POLBHTT | |
| SCHEMBL30675225 | 0.83 | PTGDR2 (0.45) | POLBHTTKDM4ECYP2C9 | |
| SCHEMBL28626906 | 0.83 | PTGDR2 (0.45) | POLBHTTKDM4ECYP2C9 | |
| SCHEMBL20398438 | 0.77 | ACHE (0.44) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL20398533 | 0.77 | ACHE (0.44) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL30434681 | 0.77 | ACHE (0.44) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL28621893 | 0.74 | POLB (0.43) | LMNAMAPTPOLBHTTKMT2A | |
| SCHEMBL29371589 | 0.73 | ELANE (0.44) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL20398543 | 0.73 | ELANE (0.44) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL22478566 | 0.72 | ALDH1A1 (0.67) | LMNAPOLBKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429332-B | 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs | 长春工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-113429332-A | 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs | 长春工业大学 | 2021-09-24 | — | — | CN | disclosed |