SCHEMBL28629170

SCHEMBL28629170

CC(C)(C)c1cccc2c1[CH]c1cccc(C(C)(C)C)c1-2

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPN5 P54829 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044050 0.87 GABRA1 (0.43) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL2045383 0.82 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL726454 0.82 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL2050307 0.79 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL2047275 0.79 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1028544 0.77 ALDH1A1 (0.33) CA2ALDH1A1TSHRTDP1
SCHEMBL28623994 0.72 ALDH1A1 (0.42) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL215708 0.72 ALDH1A1 (0.42) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL28614786 0.72 ALDH1A1 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL4468064 0.72 ALDH1A1 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302213-A Catalyst for olefin polymerization and process for producing olefin polymer containing polar group 国立大学法人东京大学 2021-08-24 CN disclosed