SCHEMBL28629307

SCHEMBL28629307

O=Cc1c(C=O)c2cc([N+](=O)[O-])cc3c(C=O)c(C=O)c4cc([N+](=O)[O-])cc1c4c23

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.44
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
ERN1 O75460 2/20 0.40
HTT P42858 2/20 0.39
POLB P06746 2/20 0.39
PTPN1 P18031 1/20 0.39
LMNA P02545 3/20 0.38
VCAM1 P19320 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.37
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28009963 0.91 TSHR (0.45) TSHRALDH1A1ERN1HTTPOLB
SCHEMBL2824579 0.76 ALDH1A1 (0.50) CYP19A1TSHRALDH1A1HTTLMNA
SCHEMBL28948912 0.74 ALDH1A1 (0.52) CYP19A1TSHRALDH1A1ERN1HTT
SCHEMBL8533694 0.74 HTT (0.57) CYP19A1TSHRALDH1A1ERN1HTT
SCHEMBL8484182 0.74 ALDH1A1 (0.61) CYP19A1TSHRALDH1A1ERN1HTT
SCHEMBL21068952 0.74 CYP19A1 (0.44) CYP19A1TSHRALDH1A1ERN1HTT
SCHEMBL7310925 0.74 TSHR (0.52) CYP19A1TSHRALDH1A1ERN1HTT
SCHEMBL11299792 0.71 S100A4 (0.53) TSHRALDH1A1ERN1POLBPTPN1
Formaldehyde SCHEMBL27742852 0.70 CYP19A1 (0.72) CYP19A1TSHRALDH1A1HTTPOLB
SCHEMBL1548019 0.70 CYP19A1 (0.50) CYP19A1TSHRALDH1A1ERN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115360349-A Organic electrode material, positive electrode, flexible positive electrode and battery 蜂巢能源科技股份有限公司 2022-11-18 CN claimed
CN-113292725-A Pyrazine two-dimensional organic porous material and preparation method and application thereof 南京工业大学 2021-08-24 CN claimed
CN-115360349-A Organic electrode material, positive electrode, flexible positive electrode and battery 蜂巢能源科技股份有限公司 2022-11-18 CN disclosed