Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310925 | 0.78 | TSHR (0.52) | HTTLMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL8018399 | 0.77 | LMNA (0.67) | HTTLMNAMEN1KMT2AXDH | |
| SCHEMBL2824579 | 0.76 | ALDH1A1 (0.50) | HTTLMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL9550826 | 0.75 | MEN1 (0.69) | HTTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28629307 | 0.74 | CYP19A1 (0.44) | HTTLMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL21068952 | 0.74 | CYP19A1 (0.44) | HTTLMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL28948912 | 0.74 | ALDH1A1 (0.52) | HTTLMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL8484182 | 0.74 | ALDH1A1 (0.61) | HTTMEN1KMT2ACYP19A1TSHR | |
| SCHEMBL5773404 | 0.74 | ERN1 (0.58) | HTTLMNAMEN1KMT2AXDH | |
| SCHEMBL8528596 | 0.73 | HTT (0.68) | HTTLMNAMEN1KMT2AXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675105-B1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET SA (FR) | 1998-12-23 | — | — | EP | claimed |
| EP-0675105-A1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET S.A. (FR) | 1995-10-04 | — | — | EP | claimed |
| EP-0675105-B1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET SA (FR) | 1998-12-23 | — | — | EP | disclosed |
| US-5693311-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET S.A. (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0675105-A1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET S.A. (FR) | 1995-10-04 | — | — | EP | disclosed |