SCHEMBL2862945

SCHEMBL2862945

Cc1ccc(C(O)(c2ccc(C)cc2)C(O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.58
MAPK1 P28482 2/20 0.58
HIF1A Q16665 1/20 0.58
CYP19A1 P11511 4/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HTT P42858 2/20 0.47
XBP1 P17861 1/20 0.47
PTGS2 P35354 1/20 0.44
HCRTR1 O43613 1/20 0.42
HCRTR2 O43614 1/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
BCL2 P10415 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763633 0.89 TSHR (0.55) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL2239969 0.89 MEN1 (0.58) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL2860836 0.87 TSHR (0.74) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL12679 0.81
SCHEMBL6203955 0.81
SCHEMBL7932610 0.81 NPSR1 (0.53) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL2862802 0.80 MEN1 (0.50) MEN1KMT2ATSHRMAPK1CYP19A1
SCHEMBL4456983 0.80 CES2 (0.46) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL7768882 0.80 MEN1 (0.50) MEN1KMT2ATSHRMAPK1CYP19A1
SCHEMBL6206704 0.80 CES2 (0.46) MEN1KMT2ATSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
EP-3510058-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME The University of Massachusetts (US) 2019-07-17 EP disclosed
US-20190202953-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS 2019-07-04 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
WO-2018039325-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS (US) 2018-03-01 WO disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed
US-4352723-A ULTRAVIOLET RADIATION; PHOTOINITIATOR AND AROMATIC PINACOL W. R. GRACE & CO. (US) 1982-10-05 US disclosed
US-4288527-A Dual UV/thermally curable acrylate compositions with pinacol W. R. GRACE & CO. (US) 1981-09-08 US disclosed
US-4135047-A PREPARATION OF THIOETHERS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1979-01-16 US disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed