(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28629609

C(=C\c1ccccc1)\c1ccccc1.CC(C)(O)C(C)(C)O.OB(O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CYP2C19 P33261 1/20 0.46
TTR P02766 1/20 0.45
ALOX5 P09917 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
CHAT P28329 2/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
EGFR P00533 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL28271366 1.00 CA1 (0.52) CA1CYP2C19TTRALOX5PTGS1
Styrylboronic Acid SCHEMBL28579652 0.85 CA1 (0.76) CA1CYP2C19TTRALOX5PTGS1
Styrene SCHEMBL29031257 0.83 ALDH1A1 (0.58) CA1CYP2C19PTGS2ALDH1A1MAPT
Boric Acid SCHEMBL30567943 0.81 CYP2C19 (0.46) CA1CYP2C19TTRALOX5PTGS1
Boric Acid SCHEMBL29141876 0.79 CA1 (0.41) CA1CYP2C19TTRALOX5PTGS1
Biphenyl SCHEMBL29104147 0.78 MGLL (0.48) CA1CYP2C19ALDH1A1MAPTSMN1; SMN2
Benzene SCHEMBL6931516 0.77 THRB (0.35) ALDH1A1TDP1LMNA
(Z)-1,2-Diphenylethene SCHEMBL29134000 0.77 MAOB (0.69) CA1TTRALOX5PTGS1PTGS2
Benzene SCHEMBL28200434 0.77 THRB (0.35) ALDH1A1TDP1LMNA
Phenol SCHEMBL27967517 0.76 CA4 (0.55) CA1ALDH1A1MEN1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113307727-A Piezochromic tetraphenyl vinyl compound and preparation method and application thereof 河北科技大学 2021-08-27 CN disclosed