Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198589 | 0.98 | MMP13 (0.40) | GPR132MMP13MMP2MMP1MMP9 | |
| SCHEMBL2860292 | 0.91 | ALDH1A1 (0.42) | KDM4EMEN1ALDH1A1KMT2APPARD | |
| SCHEMBL1198663 | 0.88 | MMP13 (0.44) | MMP13KDM4EMEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2857015 | 0.87 | PPARD (0.38) | KDM4EMEN1ALDH1A1KMT2APPARD | |
| SCHEMBL2859042 | 0.87 | ALKBH1 (0.49) | MMP13MMP2MMP1MMP9KDM4E | |
| SCHEMBL12876129 | 0.86 | KMT2A (0.45) | MMP13MMP2MMP1MMP9KMT2A | |
| SCHEMBL2868652 | 0.86 | ALKBH1 (0.45) | MMP13MMP2MMP1MMP9KDM4E | |
| SCHEMBL1198613 | 0.85 | ALDH1A1 (0.42) | KDM4EMEN1ALDH1A1KMT2AEGLN1 | |
| SCHEMBL12876610 | 0.85 | PPARD (0.39) | KDM4EMEN1ALDH1A1KMT2APPARD | |
| SCHEMBL2861490 | 0.85 | ALKBH1 (0.44) | KDM4EMEN1ALDH1A1KMT2APPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264017-A1 | HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-12-22 | — | — | EP | disclosed |