Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | SMO | Q99835 | 3/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12876610 | 0.98 | PPARD (0.39) | PPARDALOX5APALDH1A1KDM4EMEN1 | |
| SCHEMBL2857017 | 0.90 | ALDH1A1 (0.36) | PPARDALOX5APALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2860292 | 0.88 | ALDH1A1 (0.42) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2863073 | 0.87 | GPR132 (0.39) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1198589 | 0.85 | MMP13 (0.40) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2868652 | 0.84 | ALKBH1 (0.45) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2861490 | 0.84 | ALKBH1 (0.44) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1198715 | 0.84 | ALDH1A1 (0.42) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2861391 | 0.83 | KDM4E (0.40) | PPARDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2859042 | 0.83 | ALKBH1 (0.49) | PPARDALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264017-A1 | HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-12-22 | — | — | EP | disclosed |