Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24315987 | 0.94 | PRKCQ (0.43) | HDAC3HTR3AHRH4RAB9AL3MBTL1 | |
| SCHEMBL30499441 | 0.88 | HDAC3 (0.46) | HDAC3HTR3AHRH4RAB9AL3MBTL1 | |
| SCHEMBL24026553 | 0.87 | KCNJ1 (0.49) | HDAC3HTR3AHRH4RAB9AL3MBTL1 | |
| SCHEMBL25666898 | 0.84 | MAPT (0.44) | HDAC3RAB9AHDAC2KDM4EALDH1A1 | |
| SCHEMBL877503 | 0.83 | HRH3 (0.43) | HRH3 | |
| SCHEMBL14658665 | 0.83 | MAPT (0.45) | HDAC3RAB9AL3MBTL1HDAC2KDM4E | |
| SCHEMBL30855580 | 0.83 | MAPT (0.45) | HDAC3RAB9AL3MBTL1HDAC2KDM4E | |
| SCHEMBL23594128 | 0.83 | CACNA2D1 (0.45) | HDAC3HRH3 | |
| SCHEMBL64138 | 0.83 | SMO (0.47) | HDAC3HTR3AHRH4RAB9AL3MBTL1 | |
| SCHEMBL1773722 | 0.82 | ADRA1A (0.50) | HDAC3HDAC2KDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075200-A | JAK inhibitor compounds for the treatment of severe pneumonia | 河南迈英诺医药科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113563345-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-111606908-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |