Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14658665 | 1.00 | MAPT (0.45) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL25666898 | 0.98 | MAPT (0.44) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL29546455 | 0.88 | HRH3 (0.49) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL5041190 | 0.86 | HRH3 (0.50) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL24315987 | 0.84 | PRKCQ (0.43) | RAB9AL3MBTL1HRH3HDAC3HDAC2 | |
| SCHEMBL28630760 | 0.83 | HDAC3 (0.46) | ALDH1A1SMN1; SMN2RAB9AKDM4EL3MBTL1 | |
| SCHEMBL29907656 | 0.83 | KMO (0.60) | MAPTALDH1A1LMNAKMOSMN1; SMN2 | |
| SCHEMBL322646 | 0.83 | KMO (0.60) | MAPTALDH1A1LMNAKMOSMN1; SMN2 | |
| SCHEMBL877503 | 0.83 | HRH3 (0.43) | KMOHRH3HCAR2 | |
| SCHEMBL10241318 | 0.83 | HDAC3 (0.52) | ALDH1A1KMOKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121509-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |