Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859089 | 0.92 | ATG4B (0.43) | GAAMEN1KMT2AATG4BCCR1 | |
| SCHEMBL2850470 | 0.91 | CCR1 (0.49) | ATG4BCCR1 | |
| SCHEMBL2852396 | 0.91 | LMNA (0.45) | GAAPOLBATG4BCCR1ENPP2 | |
| SCHEMBL2859075 | 0.91 | NPC1 (0.41) | GAAMEN1KMT2AATG4B | |
| SCHEMBL2859287 | 0.89 | TSHR (0.40) | CCR1PKM | |
| SCHEMBL2854333 | 0.86 | RAB9A (0.52) | GAAMEN1KMT2APOLBHTT | |
| SCHEMBL2861197 | 0.85 | CCR1 (0.51) | GAAMEN1KMT2ABCHEPOLB | |
| SCHEMBL2854121 | 0.83 | KMT2A (0.44) | GAAMEN1KMT2APOLBHPGD | |
| SCHEMBL2848347 | 0.83 | GAA (0.51) | GAAMEN1KMT2APOLBHTT | |
| SCHEMBL2861243 | 0.82 | KDM4E (0.52) | MEN1KMT2APOLBNCEH1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |