Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631983 | 1.00 | SIRT5 (0.44) | SIRT5CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL29211699 | 0.87 | SIRT1 (0.38) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL29211700 | 0.87 | SIRT1 (0.38) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL21814715 | 0.86 | SIRT2 (0.47) | SIRT5CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL21814716 | 0.86 | SIRT2 (0.47) | SIRT5CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL26153675 | 0.86 | SIRT2 (0.45) | SIRT5CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL28425032 | 0.85 | KLK7 (0.37) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL28974940 | 0.85 | KLK7 (0.39) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL28425028 | 0.85 | KLK7 (0.37) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL28974938 | 0.85 | KLK7 (0.39) | SIRT5SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453724-A | Sulfonylmaleimide-based linkers and corresponding conjugates | 皮埃尔法布雷医药公司 | 2021-09-28 | — | — | CN | disclosed |