Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654713 | 0.79 | HTR2C (0.45) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL515378 | 0.79 | HTR2C (0.45) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL5883357 | 0.74 | HTR2A (0.41) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL369991 | 0.71 | POLB (0.67) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL29878552 | 0.71 | POLB (0.67) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL2960423 | 0.71 | LMNA (0.40) | HTR2CHTR2APOLBTP53MAPT | |
| SCHEMBL18840154 | 0.68 | HTR2A (0.38) | HTR2CHTR2ATP53MAPTNPSR1 | |
| SCHEMBL26122002 | 0.67 | HTR2C (0.37) | HTR2CHTR2ATP53 | |
| SCHEMBL16273602 | 0.67 | HTR2C (0.44) | HTR2CHTR2APRKDCPOLBL3MBTL1 | |
| SCHEMBL5997071 | 0.67 | NQO2 (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365615-A | Compounds for inhibiting unregulated cell growth | 戈达瓦里生物炼制有限责任公司 | 2021-09-07 | — | — | CN | disclosed |