SCHEMBL369991

SCHEMBL369991

COc1cc(Br)c(Br)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
PRKDC P78527 1/20 0.58
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
MAPT P10636 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALOX5 P09917 1/20 0.48
PTGS2 P35354 1/20 0.48
CYP3A4 P08684 1/20 0.48
HTR2A P28223 6/20 0.46
TAAR1 Q96RJ0 3/20 0.46
HTR2C P28335 2/20 0.46
ACHE P22303 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29878552 1.00 POLB (0.67) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL580565 0.88 POLB (0.54) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL28799442 0.88 POLB (0.61) POLBL3MBTL1MAPTNPSR1HTR2A
SCHEMBL30202128 0.88 POLB (0.54) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL298224 0.87 POLB (0.59) POLBL3MBTL1PRKDCMAPTNPSR1
SCHEMBL27143368 0.85 POLB (0.52) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL1505362 0.83 MAPT (0.52) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL16167828 0.83 L3MBTL1 (0.56) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL13517864 0.83 L3MBTL1 (0.50) POLBL3MBTL1PRKDCLCKFYN
SCHEMBL30010118 0.83 PRKDC (0.50) POLBL3MBTL1PRKDCLCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115785466-B Preparation method and application of supermolecular material with green photooxidation effect 广州大学 2023-08-08 CN claimed
CN-115785466-A Preparation method and application of supramolecular material with green light oxidation effect 广州大学 2023-03-14 CN claimed
JP-1283293-A None JP disclosed
CN-119763719-A Method for detecting isotope distribution of compound 江苏省环境科学研究院 2025-04-04 CN disclosed
CN-119192031-A Organic compound, preparation method thereof, composite material, photoelectric device and display device 广东聚华印刷显示技术有限公司 2024-12-27 CN disclosed
CN-116023673-B Preparation method of two-dimensional and three-dimensional clover-shaped metal organic supermolecule and metal organic cage 黔南民族师范学院 2024-05-17 CN disclosed
US-20240092744-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF THE NATIONAL INSTITUTES OF PHARMACEUTICAL R&D CO., LTD (CN) 2024-03-21 US disclosed
CN-114981275-B Tricyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2023-12-19 CN disclosed
EP-4273150-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF The National Institutes of Pharmaceutical R&D Co., Ltd (CN) 2023-11-08 EP disclosed
EP-4273150-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF The National Institutes of Pharmaceutical R&D Co., Ltd (CN) 2023-11-08 EP disclosed
CN-115785466-B Preparation method and application of supermolecular material with green photooxidation effect 广州大学 2023-08-08 CN disclosed
US-20070254185-A1 Organic EL display device and organic thin film device HITACHI DISPLAYS, LTD. (JP) 2007-11-01 US disclosed
US-7244730-B2 2-iminopyrrolidine derivatives EISAI CO., LTD (JP) 2007-07-17 US disclosed
US-7244730-B2 2-iminopyrrolidine derivatives EISAI CO., LTD (JP) 2007-07-17 US disclosed
EP-1771243-A1 POROUS ARTICLE FOR DELIVERING CHEMICAL SUBSTANCES H.Lundbeck A/S (DK) 2007-04-11 EP disclosed
WO-2006000227-A1 POROUS ARTICLE FOR DELIVERING CHEMICAL SUBSTANCES H. LUNDBECK A/S (DK) 2006-01-05 WO disclosed
EP-0352182-B1 OCTASUBSTITUTED LITHIUM PHTHALOCYANINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN EPR COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1993-05-05 EP disclosed
US-4996311-A Crystal structure, stability COMMISSARIAT A. L'ENERGIE ATOMIQUE (FR) 1991-02-26 US disclosed
EP-0352182-A1 Octasubstituted lithium phthalocyanines, process for their preparation and their use in EPR COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-01-24 EP disclosed
JP-H01283293-A NOVEL METAL BISBENZOTHIOLATE COMPLEX, PRODUCTION AND SYNTHETIC INTERMEDIATE THEREOF NOK CORP 1989-11-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092744-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF GOT2, HADH, CYP4A11 POLB 2116/4885L3MBTL1 1801/4885PRKDC 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.