SCHEMBL28632518

SCHEMBL28632518

CC(C)(c1ccccc1)c1cc(-c2ccccc2)cc(C(C)(C)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.50
CNR2 P34972 4/20 0.50
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 1/20 0.50
KIF11 P52732 2/20 0.42
RXRA P19793 3/20 0.42
RXRB P28702 3/20 0.42
RXRG P48443 1/20 0.41
NR3C2 P08235 3/20 0.40
PTPN1 P18031 3/20 0.40
PTPN5 P54829 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6854492 0.88 ESR1 (0.61) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL28423705 0.86 CNR1 (0.53) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL23581093 0.84 CNR1 (0.50) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL3681495 0.84 KIF11 (0.53) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL18913698 0.83 ESR1 (0.62) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL11646120 0.81 RXRB (0.59) CNR1ALDH1A1KIF11RXRARXRB
SCHEMBL15832876 0.80 ALDH1A1 (0.58) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL6456244 0.80 ESR1 (0.65) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL3684822 0.80 ESR1 (0.67) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL35881 0.80 ESR1 (0.70) CNR1CNR2ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423742-B Bis (arylphenoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
CN-115315452-A Propylene polymers obtained using transition metal bis (phenolate) catalyst complexes and homogeneous processes for producing the same 埃克森美孚化学专利公司 2022-11-08 CN disclosed
CN-113423742-A Bis (arylphenolate) lewis base catalysts and processes thereof 埃克森美孚化学专利公司 2021-09-21 CN disclosed