SCHEMBL28633606

SCHEMBL28633606

Cc1ccc(/C(F)=C\c2ccc3ccccc3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
AKR1C3 P42330 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RELA Q04206 1/20 0.41
PTGS1 P23219 2/20 0.40
PTGS2 P35354 1/20 0.39
CYP3A4 P08684 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28633610 1.00 CYP2A6 (0.46) CYP2A6TDP1NPC1RAB9AAKR1C3
SCHEMBL28641298 1.00 CYP2A6 (0.46) CYP2A6TDP1NPC1RAB9AAKR1C3
SCHEMBL28640754 0.86 RELA (0.50) AKR1C3KDM4EALDH1A1L3MBTL1RELA
SCHEMBL28640757 0.86 RELA (0.50) AKR1C3KDM4EALDH1A1L3MBTL1RELA
SCHEMBL28644641 0.84 PTPN1 (0.56) CYP2A6AKR1C3KDM4EALDH1A1L3MBTL1
SCHEMBL28634301 0.84 PTPN1 (0.56) CYP2A6AKR1C3KDM4EALDH1A1L3MBTL1
SCHEMBL28634303 0.84 PTPN1 (0.56) CYP2A6AKR1C3KDM4EALDH1A1L3MBTL1
SCHEMBL7217591 0.82 CYP2A6 (0.47) CYP2A6TDP1NPC1RAB9AKDM4E
SCHEMBL7217583 0.82 CYP2A6 (0.47) CYP2A6TDP1NPC1RAB9AKDM4E
SCHEMBL31172199 0.75 ALDH1A1 (0.50) KDM4EALDH1A1L3MBTL1RELAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447521-B Reagent for preparing high-selectivity monofluoroolefin 中国科学院上海有机化学研究所 2021-09-03 CN disclosed