SCHEMBL28644641

SCHEMBL28644641

F/C(=C\c1ccc2ccccc2c1)c1ccc(Br)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.56
CYP2A6 P11509 1/20 0.46
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RELA Q04206 1/20 0.41
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTGS1 P23219 1/20 0.40
AKR1C3 P42330 1/20 0.40
CYP3A4 P08684 1/20 0.39
PLAU P00749 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634301 1.00 PTPN1 (0.56) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1
SCHEMBL28634303 1.00 PTPN1 (0.56) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1
SCHEMBL28640757 0.86 RELA (0.50) KDM4EALDH1A1L3MBTL1RELALMNA
SCHEMBL28640754 0.86 RELA (0.50) KDM4EALDH1A1L3MBTL1RELALMNA
SCHEMBL28633610 0.84 CYP2A6 (0.46) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1
SCHEMBL28641298 0.84 CYP2A6 (0.46) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1
SCHEMBL28633606 0.84 CYP2A6 (0.46) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1
SCHEMBL29639038 0.75 ALDH1A1 (0.53) CYP2A6KDM4EALDH1A1L3MBTL1RELA
SCHEMBL10049312 0.75 ALDH1A1 (0.53) CYP2A6KDM4EALDH1A1L3MBTL1RELA
SCHEMBL14077390 0.74 CYP2A6 (0.50) PTPN1CYP2A6KDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447521-B Reagent for preparing high-selectivity monofluoroolefin 中国科学院上海有机化学研究所 2021-09-03 CN disclosed