Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639270 | 0.91 | DHODH (0.40) | DHODHALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL28924746 | 0.91 | DHODH (0.40) | DHODHALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL12911683 | 0.88 | DHODH (0.49) | DHODHCHRNA7LCKMALT1MAPT | |
| SCHEMBL28641754 | 0.88 | DHODH (0.45) | DHODHALDH1A1CHRNA7KMT2AMEN1 | |
| SCHEMBL28645998 | 0.87 | DHODH (0.44) | DHODHALDH1A1CHRNA7KMT2AMEN1 | |
| SCHEMBL13318558 | 0.87 | DHODH (0.48) | DHODHALDH1A1CHRNA7KMT2AMEN1 | |
| SCHEMBL842004 | 0.84 | DHODH (0.51) | DHODHALDH1A1CHRNA7LCKMALT1 | |
| SCHEMBL3086322 | 0.83 | DHODH (0.49) | DHODHCHRNA7LCKMALT1MAPT | |
| SCHEMBL12911644 | 0.82 | DHODH (0.45) | DHODHALDH1A1KMT2AMEN1MALT1 | |
| SCHEMBL3200941 | 0.82 | DHODH (0.49) | DHODHALDH1A1CHRNA7TP53LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912585-B | Pyridine pyrazole-4-formamide compound based on sulfur-containing functional group and preparation method and application thereof | 江苏耘农化工有限公司 | 2021-09-17 | — | — | CN | disclosed |