Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30712298 | 0.80 | NPC1 (0.44) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL31689756 | 0.78 | KDM4E (0.53) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1159362 | 0.77 | KDM4E (0.41) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7116337 | 0.76 | L3MBTL1 (0.41) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1159383 | 0.73 | KDM4E (0.33) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL2790500 | 0.72 | PDE10A (0.64) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1159572 | 0.71 | MTNR1A (0.43) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1159388 | 0.68 | ALDH1A1 (0.47) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL11663554 | 0.67 | CES1 (0.44) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL11260717 | 0.67 | NPC1 (0.60) | MAPTSMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402517-A | Method for preparing lamellarin structure compound pyrrolo [2,1-a ] isoquinoline alkaloid by one-pot method | 常州大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113402517-A | Method for preparing lamellarin structure compound pyrrolo [2,1-a ] isoquinoline alkaloid by one-pot method | 常州大学 | 2021-09-17 | — | — | CN | disclosed |