Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638482 | 0.89 | KCNJ5 (0.49) | RORCKCNJ5KCNJ3WNT3ARET | |
| SCHEMBL18449668 | 0.84 | RORC (0.37) | RORCP2RX7WNT3ALMNAHTT | |
| SCHEMBL19205812 | 0.81 | NPC1 (0.45) | RORCWNT3ARETLMNANPC1 | |
| SCHEMBL28638477 | 0.79 | KCNJ5 (0.47) | RORCKCNJ5KCNJ3WNT3ARET | |
| SCHEMBL28645373 | 0.79 | KCNJ5 (0.47) | RORCKCNJ5KCNJ3WNT3ARET | |
| SCHEMBL18448279 | 0.79 | WNT3A (0.54) | RORCWNT3ARETLMNAHTT | |
| SCHEMBL18448341 | 0.78 | RORC (0.52) | RORCKCNJ5KCNJ3RETCYP2D6 | |
| SCHEMBL21133947 | 0.77 | RORC (0.44) | RORCKCNJ5KCNJ3WNT3ARET | |
| SCHEMBL19205625 | 0.77 | KCNJ5 (0.46) | RORCKCNJ5KCNJ3WNT3ALMNA | |
| SCHEMBL18449671 | 0.77 | RAB9A (0.49) | RORCWNT3ANPC1CYP2D6PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026050-B | Novel compounds as ROR gamma modulators | 格兰马克药品股份有限公司 | 2021-04-30 | — | — | CN | claimed |