SCHEMBL28634374

SCHEMBL28634374

COc1cccc([SiH2]c2ccccc2)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.45
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA12 O43570 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA4 P22748 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
TRPM8 Q7Z2W7 1/20 0.39
ABCB1 P08183 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
NQO2 P16083 1/20 0.38
POLB P06746 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706593 0.92 SMN1; SMN2 (0.44) NFE2L2CA1CA2CA7CA9
SCHEMBL23000914 0.90 ALDH1A1 (0.42) NFE2L2CA1CA2CA7CA9
SCHEMBL27949722 0.84 CA1 (0.50) NFE2L2CA1CA2CA7CA9
SCHEMBL5420856 0.83 NFE2L2 (0.39) NFE2L2CA1CA2CA7CA9
SCHEMBL5408282 0.83 NFE2L2 (0.38) NFE2L2CA1CA2CA7CA9
SCHEMBL5415668 0.83 NFE2L2 (0.38) NFE2L2CA1CA2CA7CA9
SCHEMBL5419772 0.83 SMN1; SMN2 (0.37) NFE2L2CA1CA2CA7CA9
SCHEMBL5415413 0.83 SMN1; SMN2 (0.37) NFE2L2CA1CA2CA7CA9
SCHEMBL5410049 0.80 NFE2L2 (0.37) NFE2L2CA1CA2CA7CA9
SCHEMBL5420931 0.80 NFE2L2 (0.37) NFE2L2SMN1; SMN2TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119651-A Method for producing low-silanol polyorganosiloxanes 瓦克化学股份公司 2024-05-31 CN disclosed
CN-117651641-A Metal-plated laminates containing polyorganosiloxanes 瓦克化学股份公司 2024-03-05 CN disclosed
CN-113150737-A Two-component organic silicon pouring sealant and preparation method thereof 广东莱雅新化工科技有限公司 2021-07-23 CN disclosed