SCHEMBL706593

SCHEMBL706593

COc1cccc([SiH2]c2ccc([SiH2]c3cccc(OC)c3OC)cc2)c1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.44
NFE2L2 Q16236 5/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634374 0.92 NFE2L2 (0.45) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5415413 0.90 SMN1; SMN2 (0.37) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5415668 0.90 NFE2L2 (0.38) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5408282 0.90 NFE2L2 (0.38) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5419772 0.90 SMN1; SMN2 (0.37) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL23000914 0.90 ALDH1A1 (0.42) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5420856 0.90 NFE2L2 (0.39) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5410049 0.87 NFE2L2 (0.37) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5416843 0.86 NFE2L2 (0.36) SMN1; SMN2NFE2L2CA12CA1CA2
SCHEMBL5420931 0.80 NFE2L2 (0.37) SMN1; SMN2NFE2L2MAPK1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4408906-B1 METHOD FOR PREPARING LOW-SILANOL POLYORGANOSILOXANES WACKER CHEMIE AG (DE) 2025-05-28 EP disclosed
EP-4384392-B1 METAL-PLATED LAMINATES CONTAINING POLYORGANOSILOXANES WACKER CHEMIE AG (DE) 2025-03-19 EP disclosed
US-20240392072-A1 METHOD FOR PREPARING LOW-SILANOL POLYORGANOSILOXANES WACKER CHEMIE AG (DE) 2024-11-28 US disclosed
EP-4408906-A1 METHOD FOR PREPARING LOW-SILANOL POLYORGANOSILOXANES Wacker Chemie AG (DE) 2024-08-07 EP disclosed
EP-4384392-A1 METAL-PLATED LAMINATES CONTAINING POLYORGANOSILOXANES Wacker Chemie AG (DE) 2024-06-19 EP disclosed
WO-2023051912-A1 METHOD FOR PREPARING LOW-SILANOL POLYORGANOSILOXANES WACKER CHEMIE AG (DE) 2023-04-06 WO disclosed
WO-2023016649-A1 METAL-PLATED LAMINATES CONTAINING POLYORGANOSILOXANES WACKER CHEMIE AG (DE) 2023-02-16 WO disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed