Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435626 | 0.78 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27865607 | 0.75 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28435627 | 0.74 | LMNA (0.51) | CA1CA2MMP1MMP2MMP9 | |
| Acrylic Acid Methyl Ester SCHEMBL29076835 | 0.73 | CA1 (0.54) | CA1CA2PTGS2PTGS1POLB | |
| Acrylic Acid SCHEMBL30115050 | 0.72 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL16013706 | 0.72 | MMP1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29288589 | 0.70 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27415618 | 0.68 | MMP1 (0.50) | MMP1MMP2MMP9MMP13MMP8 | |
| SCHEMBL2975869 | 0.67 | THRB (0.55) | MEN1ALDH1A1KMT2AHPGDTGM2 | |
| SCHEMBL2492594 | 0.67 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461632-B | Preparation method of methyl 3- ((4-fluorophenyl) sulfonyl) -4-hydroxy-2-methylthiazolidine-2-carboxylate | 上海应用技术大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-113461632-A | Preparation method of methyl 3- ((4-fluorophenyl) sulfonyl) -4-hydroxy-2-methylthiazolidine-2-carboxylate | 上海应用技术大学 | 2021-10-01 | — | — | CN | disclosed |