SCHEMBL28634601

SCHEMBL28634601

Cc1ccc(N(c2ccccc2)S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.66
PKM P14618 1/20 0.63
CA12 O43570 1/20 0.62
CA9 Q16790 1/20 0.62
ESR1 P03372 1/20 0.59
MAPT P10636 2/20 0.53
MCOLN3 Q8TDD5 1/20 0.53
CNR2 P34972 4/20 0.50
CNR1 P21554 3/20 0.50
C5AR1 P21730 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.49
NPSR1 Q6W5P4 2/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 1/20 0.49
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
PTPRC P08575 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702995 0.98 ALDH1A1 (0.63) ALDH1A1PKMCA12CA9ESR1
SCHEMBL3697451 0.94 PKM (0.71) ALDH1A1PKMCA12CA9ESR1
SCHEMBL3886338 0.88 ALDH1A1 (0.62) ALDH1A1PKMCA12CA9ESR1
SCHEMBL3701001 0.88 MAPT (0.67) ALDH1A1PKMCA12CA9ESR1
SCHEMBL812682 0.88 PKM (0.79) ALDH1A1PKMCA12CA9ESR1
SCHEMBL6158839 0.85 ALDH1A1 (0.59) ALDH1A1PKMCA12CA9ESR1
SCHEMBL8656925 0.85 PKM (0.63) ALDH1A1PKMCA12CA9ESR1
SCHEMBL6158969 0.84 ALDH1A1 (0.58) ALDH1A1PKMCA12CA9ESR1
SCHEMBL28380035 0.84 NPSR1 (0.69) ALDH1A1PKMCA12CA9ESR1
SCHEMBL6158520 0.84 ALDH1A1 (0.61) ALDH1A1PKMCA12CA9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641472-B Recording material and recording sheet 日本曹达株式会社 2021-07-27 CN disclosed