Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924135 | 0.90 | CRBN (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL28924134 | 0.90 | CRBN (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL26916149 | 0.89 | CRBN (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL12062407 | 0.85 | HCAR1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL4112401 | 0.84 | HCAR1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL30494869 | 0.83 | JAK2 (0.34) | SLC28A1SLC28A2SLC29A1SLC28A3MAPT | |
| SCHEMBL26683509 | 0.79 | KDM4C (0.45) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL26683632 | 0.79 | CRBN (0.41) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL30588516 | 0.78 | HTR6 (0.39) | CRBNDDB1KDM4C | |
| SCHEMBL26114188 | 0.78 | HTR6 (0.39) | CRBNDDB1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-12454521-B2 | Targeted protein degradation | C4 THERAPEUTICS, INC. | 2025-10-28 | — | — | US | disclosed |
| US-20220372016-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2022-11-24 | — | — | US | disclosed |
| CN-113453679-A | Targeted protein degradation | C4医药公司 | 2021-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | PSMC3, PSMA6, ADRM1 | SLC28A1 4358/4885SLC28A2 4489/4885SLC29A1 4666/4885 |
| US-20220372016-A1 | TARGETED PROTEIN DEGRADATION | STUB1, MDM2, UBE3A | SLC28A1 4656/4885SLC28A2 4753/4885SLC29A1 4486/4885 |
| US-12454521-B2 | Targeted protein degradation | STUB1, MDM2, UBE3A | SLC28A1 4656/4885SLC28A2 4753/4885SLC29A1 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.