Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517973 | 0.69 | CFTR (0.36) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1466632 | 0.66 | DRD2 (0.35) | ALDH1A1 | |
| SCHEMBL13362359 | 0.61 | CFTR (0.31) | — | |
| SCHEMBL5151822 | 0.59 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHR | |
| SCHEMBL8281162 | 0.59 | LMNA (0.51) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2596428 | 0.58 | ALDH1A1 (0.53) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4272423 | 0.58 | KMT2A (0.41) | SMN1; SMN2 | |
| SCHEMBL27773868 | 0.58 | MAPT (0.36) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28141932 | 0.57 | ALOX15 (0.42) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL21723240 | 0.57 | ALDH1A1 (0.51) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693701-B | Modulators of ATP-binding cassette transporters | 弗特克斯药品有限公司 | 2021-08-10 | — | — | CN | disclosed |