Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634819 | 1.00 | RAB9A (0.47) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL4920563 | 0.75 | MAPT (0.56) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL27351751 | 0.75 | KDM5A (0.67) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28619676 | 0.72 | BCL2L1 (0.65) | KMT2AALDH1A1TNFRSF1APTGS1BCL2L1 | |
| SCHEMBL8918074 | 0.71 | MMP1 (0.69) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL8918070 | 0.71 | MMP1 (0.69) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL27915328 | 0.70 | KDM4E (0.52) | NPC1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3586872 | 0.70 | NEU3 (0.58) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL2345304 | 0.69 | HCAR3 (0.57) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL15550168 | 0.69 | PTGS1 (0.57) | TNFRSF1AALOX5PTGS1PTGS2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |