SCHEMBL28635537

SCHEMBL28635537

NCC(=O)OC1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 2/20 0.44
▸ IGF2R P11717 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ TYR P14679 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ SLC28A3 Q9HAS3 3/20 0.40
▸ PTPN1 P18031 1/20 0.40
▸ GJA1 P17302 1/20 0.40
▸ GJB2 P29033 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27494277 0.98 IGF2R (0.44) LGALS8IGF2RL3MBTL1GAATYR
SCHEMBL13098010 0.84 IGF2R (0.43) LGALS8IGF2RL3MBTL1GAATYR
SCHEMBL229813 0.84 LGALS8 (0.56) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL17938837 0.84 L3MBTL1 (0.46) LGALS8IGF2RL3MBTL1GAATYR
SCHEMBL27775938 0.84 L3MBTL1 (0.46) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL16934775 0.84 L3MBTL1 (0.46) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL6410535 0.84 LGALS8 (0.56) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL1097983 0.84 LGALS8 (0.56) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL28909059 0.84 L3MBTL1 (0.46) LGALS8L3MBTL1GAATYRMAPT
SCHEMBL17080338 0.84 L3MBTL1 (0.46) LGALS8L3MBTL1GAATYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113543848-A Donor T cells with killer switch 美国杰特贝林生物制品有限公司 2021-10-22 — — CN disclosed
CN-113518825-A Hematopoietic stem cell gene therapy for WISKOTT-ALDRICH syndrome 美国杰特贝林生物制品有限公司 2021-10-19 — — CN disclosed
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