SCHEMBL13098010

SCHEMBL13098010

NCC(=O)CCC(=O)OC1OC(CO)C(O)C(O)C1O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ IGF2R P11717 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ LGALS8 O00214 2/20 0.39
▸ GAA P10253 1/20 0.38
▸ TYR P14679 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ GJA1 P17302 1/20 0.38
▸ GJB2 P29033 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SLC28A3 Q9HAS3 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17938837 0.89 L3MBTL1 (0.46) IGF2RL3MBTL1LGALS8GAATYR
SCHEMBL27494277 0.86 IGF2R (0.44) IGF2RL3MBTL1LGALS8GAATYR
SCHEMBL28635537 0.84 LGALS8 (0.44) IGF2RL3MBTL1LGALS8GAATYR
SCHEMBL30705725 0.83 KDM4E (0.44) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL2786780 0.82 SLC28A3 (0.45) L3MBTL1LGALS8MAPTSLC28A3ALDH1A1
SCHEMBL17080327 0.80 PYGB (0.51) L3MBTL1LGALS8GAAMAPTSLC28A3
SCHEMBL8431126 0.80 PYGB (0.51) L3MBTL1LGALS8GAAMAPTSLC28A3
SCHEMBL17080326 0.80 PYGB (0.51) L3MBTL1LGALS8GAAMAPTSLC28A3
SCHEMBL546798 0.80 PYGB (0.51) L3MBTL1LGALS8GAAMAPTSLC28A3
SCHEMBL1098586 0.79 LGALS8 (0.45) L3MBTL1LGALS8GAATYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100273725-A1 Novel compounds useful in therapeutic and cosmetic methods PHOTODERMA SA (CH) 2010-10-28 — — US disclosed
US-20100273725-A1 Novel compounds useful in therapeutic and cosmetic methods PHOTODERMA SA (CH) 2010-10-28 — — US disclosed
WO-2009077960-A1 NOVEL COMPOUNDS USEFUL IN THERAPEUTIC AND COSMETIC METHODS PHOTODERMA SA (CH) 2009-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100273725-A1 Novel compounds useful in therapeutic and cosmetic methods ALAD, CUTA, AADAT IGF2R 2947/4885L3MBTL1 4255/4885LGALS8 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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