SCHEMBL29303802

SCHEMBL29303802

Nc1cccc(-c2cccc(-c3ccc4ccccc4c3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.61
ALDH1A1 P00352 4/20 0.58
CYP3A4 P08684 3/20 0.58
HSD17B10 Q99714 2/20 0.58
HSD17B1 P14061 2/20 0.57
HSD17B2 P37059 2/20 0.57
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HBB P68871 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
PRMT1 Q99873 1/20 0.49
CYP1A2 P05177 2/20 0.48
MAP4K4 O95819 2/20 0.48
CYP17A1 P05093 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30469312 0.98 MAOA (0.64) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL978013 0.98 MAOA (0.64) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL28635558 0.87 MAOA (0.57) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
Naphthylamine SCHEMBL11049846 0.87 ALDH1A1 (0.77) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL17689708 0.87 ALDH1A1 (0.56) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL18260215 0.87 HSD17B1 (0.71) ALDH1A1CYP3A4HSD17B10HSD17B1HSD17B2
SCHEMBL19752162 0.86 MAOA (0.54) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL20080558 0.85 ALDH1A1 (0.50) MAOAALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL13304735 0.85 ALDH1A1 (0.81) ALDH1A1CYP3A4HSD17B10HSD17B1HSD17B2
SCHEMBL18903007 0.83 ALDH1A1 (0.77) ALDH1A1CYP3A4HSD17B10HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237528-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-11 US disclosed
US-20240237528-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-11 US disclosed