Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625790 | 0.80 | PRNP (0.34) | — | |
| SCHEMBL28623276 | 0.76 | CA12 (0.43) | TSHR | |
| SCHEMBL28631570 | 0.72 | CYP2D6 (0.30) | — | |
| SCHEMBL11228244 | 0.65 | IMPDH2 (0.59) | PNMTCA1CA2IMPDH2IMPDH1 | |
| SCHEMBL9746966 | 0.65 | PNMT (0.52) | PNMTCA1CA2IMPDH2IMPDH1 | |
| SCHEMBL28625350 | 0.65 | — | — | |
| SCHEMBL45954 | 0.65 | CA1 (0.54) | PNMTCA1CA2IMPDH2IMPDH1 | |
| SCHEMBL29489124 | 0.65 | CA1 (0.54) | PNMTCA1CA2IMPDH2IMPDH1 | |
| SCHEMBL2166868 | 0.61 | ALDH1A1 (0.37) | CA1CA2TSHR | |
| SCHEMBL151936 | 0.61 | IMPDH2 (0.64) | CA1CA2SLC22A12IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250174-B | Naphthopyran compounds and preparation method thereof | 中国科学院兰州化学物理研究所苏州研究院 | 2021-09-10 | — | — | CN | disclosed |