Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636147 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTHTTALDH1A1KMT2A | |
| SCHEMBL28413127 | 0.86 | CA12 (0.45) | SMN1; SMN2MAPTHTTHPGDNPC1 | |
| SCHEMBL24916644 | 0.76 | PDCD1 (0.43) | MAPTHTTPDCD1CD274NPC1 | |
| SCHEMBL20920028 | 0.75 | HTT (0.42) | SMN1; SMN2MAPTHTTALDH1A1KMT2A | |
| SCHEMBL3507290 | 0.74 | LMNA (0.58) | SMN1; SMN2HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL874377 | 0.74 | TSHR (0.46) | SMN1; SMN2MAPTHTTALDH1A1TDP1 | |
| SCHEMBL24916641 | 0.74 | ACLY (0.41) | SMN1; SMN2MAPTKMT2AMEN1PDCD1 | |
| SCHEMBL13328522 | 0.74 | HTT (0.40) | SMN1; SMN2MAPTHTTALDH1A1TDP1 | |
| SCHEMBL13392286 | 0.74 | HTT (0.43) | SMN1; SMN2MAPTHTTALDH1A1TSHR | |
| SCHEMBL31093971 | 0.73 | HDAC1 (0.53) | HTTKMT2AMEN1TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248410-B | Preparation method of silver-mediated N-aroyl hydrazine compound | 湖北工业大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-113248410-A | Preparation method of silver-mediated N-arylhydrazide compound | 湖北工业大学 | 2021-08-13 | — | — | CN | disclosed |