Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636145 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4241780 | 0.82 | ALDH1A1 (0.63) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL29048566 | 0.78 | ALDH1A1 (0.69) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL874377 | 0.75 | TSHR (0.46) | SMN1; SMN2MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3507290 | 0.75 | LMNA (0.58) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL28413127 | 0.74 | CA12 (0.45) | SMN1; SMN2MAPTHTTNPC1LMNA | |
| SCHEMBL829848 | 0.74 | TSHR (0.44) | SMN1; SMN2MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29025475 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11298089 | 0.72 | TSHR (0.43) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28924147 | 0.72 | ALDH1A1 (0.51) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248410-B | Preparation method of silver-mediated N-aroyl hydrazine compound | 湖北工业大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-113248410-A | Preparation method of silver-mediated N-arylhydrazide compound | 湖北工业大学 | 2021-08-13 | — | — | CN | disclosed |