SCHEMBL28636158

SCHEMBL28636158

O=CNOC(=O)c1ccccc1Br

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.51
ALDH1A1 P00352 5/20 0.51
MAPT P10636 4/20 0.51
HPGD P15428 3/20 0.51
GAA P10253 3/20 0.51
KDM4E B2RXH2 2/20 0.51
POLB P06746 2/20 0.51
MIF P14174 1/20 0.51
USP2 O75604 1/20 0.44
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
PRNP P04156 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21801771 0.87 CYP3A4 (0.42) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL27568172 0.80 LMNA (0.58) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL28179037 0.80 ALDH1A1 (0.52) KMT2AALDH1A1HPGDKDM4EPOLB
SCHEMBL28398710 0.78 ALDH1A1 (0.54) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL4294800 0.77 SLC6A3 (0.39) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL28033367 0.77 NR4A1 (0.52) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL9466493 0.76 TSHR (0.39) ALDH1A1KDM4EPOLBNPC1LMNA
SCHEMBL28349309 0.76 KMT2A (0.44) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL29433258 0.75 TSHR (0.61) KMT2AALDH1A1MAPTHPGDGAA
SCHEMBL23659 0.75 TSHR (0.61) KMT2AALDH1A1MAPTHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113385305-A Halogenated benzohydroxamic acid collecting agent and application thereof in mineral flotation 广东省科学院资源利用与稀土开发研究所 2021-09-14 CN disclosed