Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585489 | 0.75 | ALDH1A1 (0.51) | BRD4ALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL3056489 | 0.75 | ALDH1A1 (0.46) | BRD4ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL19002374 | 0.73 | ALDH1A1 (0.53) | BRD4ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL3047809 | 0.73 | ALDH1A1 (0.42) | BRD4ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL9802957 | 0.73 | AKR1B1 (0.44) | BRD4ALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL21585490 | 0.73 | LMNA (0.71) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL17895743 | 0.70 | ALDH1A1 (0.53) | BRD4ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL23537530 | 0.68 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2POLBCYP1A2 | |
| SCHEMBL30248853 | 0.68 | PIM1 (0.48) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL7433627 | 0.68 | PIM1 (0.48) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658907-B | Sulfonyl substituted furan compounds with anti-inflammatory and immune activities and derivatives thereof | 广东药科大学 | 2021-08-13 | — | — | CN | disclosed |