Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685368 | 0.74 | LMNA (0.58) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL28636166 | 0.73 | BRD4 (0.47) | LMNAALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL21585489 | 0.71 | ALDH1A1 (0.51) | LMNAALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7681208 | 0.66 | LMNA (0.49) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL7686913 | 0.65 | LMNA (0.48) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL7685234 | 0.65 | ALOX15 (0.56) | LMNAALDH1A1HSP90AA1HSP90AB1TSHR | |
| SCHEMBL7683058 | 0.64 | LMNA (0.47) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL7689499 | 0.64 | LMNA (0.47) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL21954834 | 0.63 | MAPT (0.57) | LMNAALDH1A1HSP90AA1HSP90AB1KMT2A | |
| SCHEMBL21795161 | 0.63 | MAP1LC3B (0.67) | LMNAALDH1A1HPGDHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658907-B | Sulfonyl substituted furan compounds with anti-inflammatory and immune activities and derivatives thereof | 广东药科大学 | 2021-08-13 | — | — | CN | disclosed |
| WO-2019232664-A1 | SULFONYL SUBSTITUTED FURAN COMPOUND HAVING ANTI-INFLAMMATORY IMMUNE ACTIVITY AND DERIVATIVE THEREOF | 广东药科大学 (CN) | 2019-12-12 | — | — | WO | disclosed |