SCHEMBL28637728

SCHEMBL28637728

Oc1ccc(C2=C(c3ccc(O)cc3)C(c3ccc(O)cc3)c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ABL1 P00519 2/20 0.38
ABCB1 P08183 2/20 0.38
BCR P11274 2/20 0.38
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36
KDM1A O60341 2/20 0.36
ESR2 Q92731 6/20 0.35
ESR1 P03372 5/20 0.34
RAB9A P51151 1/20 0.33
PTPN1 P18031 1/20 0.33
BACE1 P56817 1/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
SENP1 Q9P0U3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232990 0.82 LMNA (0.41) KMT2AMEN1NPC1GAA
SCHEMBL918436 0.78 KMT2A (0.61) KMT2AMEN1KDM4EABL1ABCB1
SCHEMBL4943423 0.77 MMP3 (0.48) KMT2AMEN1KDM4EMMP3BCL2L1
SCHEMBL5176095 0.76 MEN1 (0.41) KMT2AMEN1RAB9ANPC1
SCHEMBL573085 0.73 KMT2A (0.47) KMT2AMEN1KDM4EABL1ABCB1
SCHEMBL15062364 0.73 MEN1 (0.47) KMT2AMEN1KDM4EABL1ABCB1
SCHEMBL29496707 0.73 MEN1 (0.47) KMT2AMEN1KDM4EABL1ABCB1
SCHEMBL14848377 0.72 KMT2A (0.53) KMT2AMEN1KDM4EABL1ABCB1
SCHEMBL27770267 0.72 KMT2A (0.63) KMT2AMEN1KDM4EESR1RAB9A
SCHEMBL26632876 0.68 ALDH1A1 (0.34) KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113321775-A Curable compositions and cured compositions prepared therefrom 沙特高性能聚合物和塑料全球技术公司 2021-08-31 CN disclosed