Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062973 | 0.85 | SMN1; SMN2 (0.34) | HPGDMGLL | |
| SCHEMBL25179804 | 0.81 | CA2 (0.38) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL29101914 | 0.81 | TPSAB1 (0.34) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL2730684 | 0.80 | CHRNB2 (0.39) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL1712728 | 0.77 | CA2 (0.43) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL4751947 | 0.75 | CA2 (0.42) | SIGMAR1CA2CA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL31258740 | 0.75 | CA2 (0.42) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL6069987 | 0.75 | CA2 (0.36) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL16748054 | 0.75 | HPGD (0.41) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL25821121 | 0.74 | CHRNB2 (0.42) | SIGMAR1CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307797-B | Polysubstituted quinazoline compound and application thereof | 江南大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113307797-A | Polysubstituted quinazoline compound and application thereof | 江南大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-111848584-A | Polysubstituted quinazoline compound and application thereof | 江南大学 | 2020-10-30 | — | — | CN | disclosed |