SCHEMBL1712728

SCHEMBL1712728

CC(C)OC(=O)N1CCNCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
CHKA P35790 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
CHRNB3 Q05901 1/20 0.41
CHRNA6 Q15825 1/20 0.41
CHRM5 P08912 1/20 0.38
CHRM3 P20309 1/20 0.38
SIGMAR1 Q99720 1/20 0.36
GPR119 Q8TDV5 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
HSD11B1 P28845 1/20 0.35
CYP1A2 P05177 1/20 0.35
ABHD6 Q9BV23 1/20 0.35
PLAU P00749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31258740 0.98 CA2 (0.42) CA2CA12CA1CA9CHKA
SCHEMBL14455163 0.87 USP2 (0.46) GPR119SMN1; SMN2
SCHEMBL4751947 0.86 CA2 (0.42) CA2CA12CA1CA9CHKA
SCHEMBL26317513 0.84 TSHR (0.43) GPR119SMN1; SMN2TSHRCYP1A2
SCHEMBL27979621 0.84
SCHEMBL31237085 0.84 GPR119 (0.35) GPR119TSHR
SCHEMBL25821121 0.84 CHRNB2 (0.42) CA2CA12CA1CA9CHKA
SCHEMBL25179804 0.81 CA2 (0.38) CA2CA12CA1CA9CHKA
SCHEMBL6069977 0.81 CA2 (0.38) CA2CA12CA1CA9CHKA
SCHEMBL2654623 0.80 TSHR (0.40) GPR119SMN1; SMN2TSHRHSD11B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11123683-B2 Carbon dioxide absorbent and apparatus of separating and recovering carbon dioxide KABUSHIKI KAISHA TOSHIBA (JP) 2021-09-21 US claimed
CN-109476653-A The heteroaromatic regulator of retinoids related orphan receptor y 利奥制药有限公司 2019-03-15 CN claimed
CN-109415359-A heterocyclic GPR119 agonist compounds 人类制药有限公司 2019-03-01 CN claimed
CN-109415381-A Thiazolopyridine derivatives as GPR119 agonist 人类制药有限公司 2019-03-01 CN claimed
US-20070232559-A1 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2007-10-04 US claimed
CN-101035525-A Substituted urea derivatives for the treatment of cardiac diseases CYTOKINETICS INC (US) 2007-09-12 CN claimed
US-20250388589-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO LTD (CN) 2025-12-25 US disclosed
US-20240140954-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-05-02 US disclosed
CN-111542521-B RAD51 inhibitors 赛泰尔治疗公司 2024-02-23 CN disclosed
WO-2023205914-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2023-11-02 WO disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 US disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 US disclosed
CN-112961096-B Chalcone tryptophan derivatives with cisplatin nephrotoxicity and antitumor activity 安徽医科大学 2023-05-30 CN disclosed
US-20070021494-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands SCHERING CORPORATION AND PHARMACOPEIA, INC. 2007-01-25 US disclosed
EP-1673086-A1 4-AMINOQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS PDE4 INHIBITORS GLAXO GROUP LIMITED (GB) 2006-06-28 EP disclosed
WO-2005030212-A1 4-AMINOQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS PDE4 INHIBITORS GLAXO GROUP LIMITED (GB) 2005-04-07 WO disclosed
US-4610984-A CEREBRAL INSUFFICIENCY CASSELLA AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
EP-0123977-A1 Substituted piperazin-1-yl-acetic-acid amides, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-11-07 EP disclosed
EP-0049683-A2 Imidazo-rifamycines, process for their preparation, pharmaceutical preparations containing them and their use CIBA-GEIGY AG (CH) 1982-04-14 EP disclosed
US-3947438-A Decarbonylation of quinoxalines PFIZER INC. (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021494-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands CCR1, ACKR3, CXCR1 CA2 2579/4885CA12 1004/4885CA1 1583/4885
US-20070232559-A1 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF ADORA2A, ADORA3, ADORA1 CA2 2259/4885CA12 4798/4885CA1 3627/4885
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS SREBF1, SREBF2, NR1H3 CA2 4355/4885CA12 4344/4885CA1 4426/4885
US-20240140954-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF CYP11B2, SDHA, CYP3A43 CA2 3053/4885CA12 1637/4885CA1 3060/4885
US-11123683-B2 Carbon dioxide absorbent and apparatus of separating and recovering carbon dioxide ADCY1, AOC3, ODC1 CA2 12/4885CA12 259/4885CA1 18/4885
US-20250388589-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF CYP4A11, CYP11B1, CYP2D6 CA2 445/4885CA12 396/4885CA1 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.