Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836401 | 0.76 | NPSR1 (0.44) | LMNALTA4HCALM1NPSR1L3MBTL1 | |
| SCHEMBL5297071 | 0.73 | CALM1 (0.37) | LMNALTA4HCALM1NPSR1L3MBTL1 | |
| SCHEMBL5285505 | 0.73 | LMNA (0.47) | LMNALTA4HCALM1NPSR1L3MBTL1 | |
| SCHEMBL5296926 | 0.73 | CA1 (0.40) | LMNACALM1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL5303118 | 0.72 | CALM1 (0.35) | LMNACALM1NPSR1L3MBTL1TP53 | |
| SCHEMBL5289105 | 0.71 | EEF2K (0.40) | LMNACALM1NPSR1L3MBTL1TP53 | |
| SCHEMBL5295721 | 0.69 | EEF2K (0.48) | LMNANPSR1TP53SMN1; SMN2KDM4E | |
| SCHEMBL5295679 | 0.68 | EEF2K (0.53) | LMNANPSR1TP53SMN1; SMN2KDM4E | |
| SCHEMBL5816208 | 0.67 | EEF2K (0.56) | LMNANPSR1SMN1; SMN2KDM4ECA1 | |
| SCHEMBL5283962 | 0.67 | EEF2K (0.56) | LMNANPSR1SMN1; SMN2KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480671-A | Preparation method of selenium clam polysaccharide | 广州普德生物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |