Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839374 | 0.91 | L3MBTL1 (0.41) | L3MBTL1RAB9ANPC1ADRB2ADRB1 | |
| SCHEMBL27980364 | 0.86 | CYP2C9 (0.39) | L3MBTL1RAB9ANPC1TDP1LMNA | |
| SCHEMBL5375326 | 0.84 | LMNA (0.49) | RAB9ANPC1ADRB2ADRB1ADRB3 | |
| SCHEMBL17772767 | 0.83 | TSHR (0.50) | L3MBTL1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL26328801 | 0.82 | RAB9A (0.49) | RAB9ANPC1ADRB2ADRB1ADRB3 | |
| SCHEMBL14839397 | 0.82 | ESR1 (0.42) | RAB9ANPC1TDP1TSHRLMNA | |
| SCHEMBL16072892 | 0.81 | HDAC3 (0.37) | L3MBTL1NPSR1LMNAALDH1A1 | |
| SCHEMBL28020539 | 0.77 | L3MBTL1 (0.54) | L3MBTL1RAB9ANPC1ADRB2ADRB1 | |
| SCHEMBL25439968 | 0.77 | MAPT (0.45) | RAB9ANPC1TDP1TSHRNPSR1 | |
| SCHEMBL26328803 | 0.77 | MAPK1 (0.38) | L3MBTL1RAB9ANPC1PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |