Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839397 | 0.92 | ESR1 (0.42) | LMNATDP1TSHRMAPK1SLC6A2 | |
| SCHEMBL25439968 | 0.89 | MAPT (0.45) | LMNATDP1TSHRMAPK1SLC6A2 | |
| SCHEMBL14839374 | 0.89 | L3MBTL1 (0.41) | LMNATDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL27980364 | 0.87 | CYP2C9 (0.39) | LMNATDP1KMT2ANPC1RAB9A | |
| SCHEMBL26330111 | 0.86 | NPC1 (0.49) | TDP1TSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL26328801 | 0.86 | RAB9A (0.49) | TDP1MAPK1KMT2AALDH1A1ADRB2 | |
| SCHEMBL26328803 | 0.86 | MAPK1 (0.38) | LMNATDP1TSHRMAPK1SLC6A2 | |
| SCHEMBL25439789 | 0.84 | POLB (0.48) | LMNAHIF1AKMT2AALDH1A1NPC1 | |
| SCHEMBL25439927 | 0.84 | KDM4E (0.47) | LMNATSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL28638461 | 0.84 | L3MBTL1 (0.52) | LMNATDP1TSHRALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11485987-B2 | Methods for inducing bioorthogonal reactivity | UNIVERSITY OF DELAWARE (US) | 2022-11-01 | — | — | US | disclosed |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | UNIVERSITY OF DELAWARE (US) | 2022-04-07 | — | — | US | disclosed |
| US-20210164005-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | UNIVERSITY OF DELAWARE (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210164005-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | UNIVERSITY OF DELAWARE (US) | 2021-06-03 | — | — | US | disclosed |
| US-8753795-B2 | Photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-17 | — | — | US | disclosed |
| US-8753795-B2 | Photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-17 | — | — | US | disclosed |
| EP-1712551-B1 | 3-Methyl oxetanemethanol derivatives and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2012-11-21 | — | — | EP | disclosed |
| US-20120251945-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120251945-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20070265180-A1 | 3-Methyl Oxetanemethanol Derivatives and Their Use in Perfume Compositions | INTERNATION FLAVORS & FRAGRANCES INC. | 2007-11-15 | — | — | US | disclosed |
| US-7265231-B2 | 3-methyl oxetanemethanol derivatives and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20060234882-A1 | 3-Methyl oxetanemethanol derivatives and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2006-10-19 | — | — | US | disclosed |
| EP-1712551-A1 | 3-Methyl oxetanemethanol derivatives and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120251945-A1 | PHOTORESIST COMPOSITION | H1-0, COL1A1, REV1 | LMNA 1347/4885TDP1 310/4885TSHR 2932/4885 |
| US-20070265180-A1 | 3-Methyl Oxetanemethanol Derivatives and Their Use in Perfume Compositions | PNMT, CYP51A1, MSMO1 | LMNA 3820/4885TDP1 2461/4885TSHR 4747/4885 |
| US-20060234882-A1 | 3-Methyl oxetanemethanol derivatives and their use in perfume compositions | PNMT, CYP51A1, MSMO1 | LMNA 3820/4885TDP1 2461/4885TSHR 4747/4885 |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | LMNA 3980/4885TDP1 1963/4885TSHR 1185/4885 |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | TST, CYP4F8, CYP4Z1 | LMNA 3980/4885TDP1 1963/4885TSHR 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.