SCHEMBL2863863

SCHEMBL2863863

Cc1[nH]c(Cc2cc(Cl)cc(Cl)c2)nc1-c1ccccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
KMT2A Q03164 2/20 0.40
CNR1 P21554 1/20 0.39
EGFR P00533 2/20 0.38
ERBB2 P04626 2/20 0.38
POLB P06746 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CRHR1 P34998 1/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PRNP P04156 1/20 0.37
MAPT P10636 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CXCR2 P25025 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27967693 0.89 NUDT1 (0.41) NR1H2NR1H3PRNPMAPTCXCR2
SCHEMBL2873539 0.87 MAPT (0.50) NR1H2NR1H3KMT2ACNR1EGFR
SCHEMBL26113182 0.87 NR1H2 (0.55) NR1H2NR1H3KMT2APOLBKDM4E
SCHEMBL27915186 0.86 PRNP (0.39) PRNPMAPTGAAALDH1A1
SCHEMBL28813824 0.86 CRHR1 (0.40) EGFRERBB2CRHR1HSP90AA1
SCHEMBL2867432 0.86 SLC9A1 (0.37) EGFRERBB2PRNPMAPTCXCR2
SCHEMBL27967758 0.86 PDE5A (0.37) KMT2APOLBPRNPMAPTHTT
SCHEMBL26113421 0.85 ADORA2A (0.44) NR1H2NR1H3KMT2ACRHR1ALDH1A1
SCHEMBL26111005 0.84 NR1H2 (0.40) NR1H2NR1H3KMT2AKDM4ECRHR1
SCHEMBL2864047 0.83 KDM4E (0.51) NR1H2NR1H3KMT2AEGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102119240-B Surface treating agent for copper or copper alloy and use thereof SHIKOKU CHEM 2014-07-30 CN disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed