Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL28124416 | 0.93 | — | — | |
| Imidazole SCHEMBL28125230 | 0.93 | — | — | |
| Imidazole SCHEMBL28271862 | 0.93 | — | — | |
| Imidazole SCHEMBL28031289 | 0.93 | — | — | |
| Imidazole SCHEMBL28205821 | 0.93 | — | — | |
| Imidazole SCHEMBL30382963 | 0.93 | — | — | |
| Imidazole SCHEMBL28744226 | 0.93 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL1331920 | 0.93 | — | — | |
| Imidazole SCHEMBL2635292 | 0.93 | — | — | |
| Imidazole SCHEMBL1331382 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549196-B | Fluorenyl conjugated polymer and preparation method of electric storage device thereof | 黑龙江大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-113549196-A | Fluorenyl conjugated polymer and preparation method of electric storage device thereof | 黑龙江大学 | 2021-10-26 | — | — | CN | disclosed |