Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000301 | 0.84 | ACHE (0.42) | CA12CA9MGAT2SENP1MAPT | |
| SCHEMBL12169128 | 0.84 | ACHE (0.42) | CA12CA9MGAT2SENP1MAPT | |
| SCHEMBL17239814 | 0.80 | SENP1 (0.36) | CHEK1WEE1SENP1MAPTKDM4E | |
| SCHEMBL286665 | 0.80 | SENP1 (0.36) | CHEK1WEE1SENP1MAPTKDM4E | |
| SCHEMBL7897924 | 0.80 | ALDH1A1 (0.44) | MMP3MGAT2MAPTKDM4EMEN1 | |
| SCHEMBL286571 | 0.80 | MAOB (0.56) | MAPTKDM4EMEN1LMNAPOLB | |
| SCHEMBL1419877 | 0.79 | ESR2 (0.50) | MAPTKDM4EMEN1KMT2AESR1 | |
| SCHEMBL286649 | 0.79 | ESR2 (0.50) | MAPTKDM4EMEN1KMT2AESR1 | |
| SCHEMBL13050075 | 0.78 | SENP1 (0.34) | SENP1MAPTKDM4EMEN1LMNA | |
| SCHEMBL7003386 | 0.77 | CA2 (0.49) | CA12CA2CA3CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020716-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | Forum Pharmaceuticals Inc. (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-3020716-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | Forum Pharmaceuticals Inc. (US) | 2016-05-18 | — | — | EP | disclosed |
| US-20150322069-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322069-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-11-12 | — | — | US | disclosed |
| EP-2617420-B1 | Phenoxymethyl heterocyclic compounds | FORUM PHARMACEUTICALS INC (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-2617420-B1 | Phenoxymethyl heterocyclic compounds | FORUM PHARMACEUTICALS INC (US) | 2015-09-23 | — | — | EP | disclosed |
| US-8946222-B2 | Phenoxymethyl heterocyclic compounds | FORUM PHARMACEUTICALS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8946222-B2 | Phenoxymethyl heterocyclic compounds | FORUM PHARMACEUTICALS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| EP-2617420-A1 | Phenoxymethyl heterocyclic compounds | Envivo Pharmaceuticals, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| EP-2617420-A1 | Phenoxymethyl heterocyclic compounds | Envivo Pharmaceuticals, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| EP-2427454-B1 | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS INC (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-2427454-B1 | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS INC (US) | 2013-03-20 | — | — | EP | disclosed |
| US-8343973-B2 | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-8343973-B2 | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| CN-102459242-A | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS INC | 2012-05-16 | — | — | CN | disclosed |
| EP-2427454-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100292238-A1 | Phenoxymethyl Heterocyclic Compounds | FMR LLC | 2010-11-18 | — | — | US | disclosed |
| US-20100292238-A1 | Phenoxymethyl Heterocyclic Compounds | FMR LLC | 2010-11-18 | — | — | US | disclosed |
| WO-2010128995-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128995-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322069-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | PDE3A, PDE2A, PDE5A | MMP3 139/4885CA12 2975/4885CA2 647/4885 |
| US-20100292238-A1 | Phenoxymethyl Heterocyclic Compounds | PDE3A, PDE2A, PDE5A | MMP3 139/4885CA12 2975/4885CA2 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.