SCHEMBL2863940

SCHEMBL2863940

CC1=Cc2cccc(C)c2C1[Zr](Cl)(Cl)(=C(c1ccccc1)c1ccccc1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
KCNK9 Q9NPC2 1/20 0.31
TP53 P04637 1/20 0.30
THRB P10828 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2861547 0.89 CA12 (0.31) LMNAKCNK9
SCHEMBL2857313 0.87 S1PR4 (0.31)
SCHEMBL2867840 0.86 LMNA (0.32) LMNAKCNK9TP53THRBSMN1; SMN2
SCHEMBL2861052 0.86
SCHEMBL2860772 0.86 ALDH1A1 (0.31) LMNAKCNK9TP53THRBSMN1; SMN2
SCHEMBL2866637 0.86 KCNK3 (0.31) KCNK9
SCHEMBL2870736 0.84
SCHEMBL2868387 0.84
SCHEMBL2860436 0.83 LMNA (0.31) LMNAKCNK9
SCHEMBL2863640 0.80 KCNK9 (0.30) KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed