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SCHEMBL28639436

SCHEMBL28639436

CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c(F)c(F)c(F)c(F)c1F)C(=O)NC(CCCCOC(N)=O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 3/20 0.46
▸ NPY4R P50391 6/20 0.46
▸ CCKBR P32239 2/20 0.45
▸ NPY1R P25929 3/20 0.45
▸ NPY2R P49146 2/20 0.45
▸ NPY5R Q15761 2/20 0.45
▸ CTSL P07711 2/20 0.44
▸ CTSS P25774 3/20 0.44
▸ CTSB P07858 1/20 0.44
▸ CTSK P43235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28639434 1.00 REN (0.46) RENNPY4RCCKBRNPY1RNPY2R
SCHEMBL28652457 0.93 CTSS (0.48) NPY4RNPY1RNPY2RNPY5RCTSS
SCHEMBL28652461 0.93 CTSS (0.48) NPY4RNPY1RNPY2RNPY5RCTSS
SCHEMBL22117410 0.92 REN (0.48) RENNPY4RCCKBRNPY1RNPY2R
SCHEMBL22117409 0.92 REN (0.48) RENNPY4RCCKBRNPY1RNPY2R
SCHEMBL31679022 0.91 CTSL (0.51) RENNPY4RCCKBRNPY1RNPY2R
SCHEMBL31679016 0.89 KLK7 (0.50) NPY4RCCKBRCTSLCTSS
SCHEMBL28644135 0.86 REN (0.59) RENCCKBRCTSLCTSSCTSB
SCHEMBL28644132 0.86 REN (0.59) RENCCKBRCTSLCTSSCTSB
SCHEMBL22117421 0.85 REN (0.54) RENNPY4RCCKBRNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113544138-A Mitochondrial targeting peptides 隐形生物治疗公司 2021-10-22 — — CN disclosed
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